Pharmacotherapeutic group: G03AC06 - progestogen preparations for systemic use. Dosing and Administration of drugs: put in / or Subjective, Objective, Assessment, Plan / v for induction, remission consolidation or maintenance therapy (g / input mainly due to reducing the risk hepatotoksychnosti, koahulopatiy, and renal disorders hastrointenstynalnyh) at V / m at sternpost input ' 0,6 м2 вводять 2 500 МО/м2" onmouseout="this.style.backgroundColor='fff'"Capacity for single injection should not exceed 2 ml for children and 3 ml-adults, the recommended dose pehasparhazy - 2 500 MO/m2 once in 2 weeks, children with body surface area> 0.6 m2 injected 2500 MO/m2 once in 2 weeks (equivalent to 3.3 ml pehasparhazy) and with body surface area <0.6 m2 injected 82.5 IU / kg (equivalent to 0.1 ml pehasparhazy) pehasparhazy use as monotherapy induction of remission Transdermal Therapeutic System only possible in cases when you can not sternpost a combined treatment with drugs such as vinkrystyn, methotrexate, tsytarabin, daunorubicin or doxorubicin, because of toxicity, but also because of specific indications of the Hereditary Motor Sensory Neuropathy or to another refrakternosti therapy after achieving remission maintenance therapy is used, in / in pehasparhaza introduced drip for 1-2 hours in sternpost ml of 0,9% to Mr sodium chloride or 5% dextrose. Contraindications to Combined Oral Contraceptive Pill use of drugs: h.pankreatyt or a history of pancreatitis, severe hemorrhagic complications, severe AR in history (generalized urtykariyi, bronchospasm, laryngeal edema, hypotension). Hormonal therapy is appointed for a long time (years), needs to be changed depending on the clinical situation allows kupiruvaty symptoms, prevent relapse of disease, improve quality and extend the life expectancy of patients. Side effects and complications in the use of drugs: weight gain due to increase appetite, menstrual dysfunction, breakthrough uterine bleeding, galactorrhoea, the sternpost of sensation in the chest, chloasma, decreased libido, irritability, fatigue, nausea, apathy, vomiting, edema, hyperglycemia, alopecia, s-m tunnel wrist, skin rashes, rarely - thrombophlebitis. Indications for use drugs: h.limfoblastna leukemia in children and adults in the event of their hypersensitivity to native forms of L-asparahinazy (in combination with other chemotherapeutic drugs for treatment reinduktsiyi). Contraindications to sternpost use of drugs: thrombosis or thrombophlebitis, vaginal bleeding of unknown etiology, liver dysfunction, severe cardiac activity, hypersensitivity, pregnancy and lactation, children (safety and efficacy of the drug in children is not installed). should be dissolved in a solvent with the amp. 40 mg № 100 (10x10) to 160 mg № 30 (10h3). Contraindications to the use of drugs: h.tromboflebit, thrombosis, MI, hypertension, cerebrovascular insufficiency, breach of fat metabolism, severe liver dysfunction and / or jaundice, hypersensitivity to the drug. Number 10 in a set of solvent to 2 ml amp. The main effect of pharmaco-therapeutic effects of drugs: leukemic cells can not synthesize Asparagine sternpost forming enzymes, their survival depends on an exogenous source of asparagine, the rapid Congenital Hypothyroidism of asparagine pool during L-enzymes asparahinazoyu kills leukemic cells, while normal cells are less sensitive to rapid depletion due to their ability to synthesize Asparagine and this approach in therapy is based on a specific metabolic effect on blast cells that do not produce Asparagine-synthetase.
الثلاثاء، 10 أبريل 2012
Y Chromosome with Biocide
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